PreclinicalResearch compound

Selank

Tuftsin analog, anxiolytic nootropic

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Selank vial

WHAT IS SELANK?

Detailed overview

Selank is a C-terminally extended analog of tuftsin (Thr-Lys-Pro-Arg), registered as an anxiolytic in Russia. Available in two forms: subcutaneous injection (research protocol) and intranasal spray (Russian clinical practice primary route).

Type

Tuftsin analog

Structure

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Status

Registered RU

Storage

2–8°C

Source

Placeholder, image later

Cognitive function

BDNF and NGF rise, supporting synaptic plasticity, LTP and the formation of new neural connections. Attention, working memory and task-switching measurably improve within 2–4 weeks. Neuroprotection: oxidative stress, excitotoxicity and glial inflammation drop, especially in aged, stressed or trauma-exposed brains. Mood stabilization and anxiety reduction follow via HPA-axis modulation. Effects are cumulative.

Sleep quality

Deep-sleep (N3) phases lengthen, critical for GH release and memory consolidation. The cortisol rhythm normalizes: evening levels drop, morning rise returns. Sleep onset is faster, waking is more rested. GABAergic and serotonergic modulation reduces anxiety, dreams can become more vivid. Over time, symptoms of chronic sleep debt (memory, mood, immunity) improve. Best paired with an afternoon / evening dose.

Data console

Lab data

/lab/molecular-data.jsonLIVE
> ClassificationTuftsin analog
> StructureThr-Lys-Pro-Arg-Pro-Gly-Pro
> Molecular weightN/A
> Target area-
> Storage2–8°C
> Stability~30 days reconstituted

Research indications

Investigated uses and mechanisms

Memory & learning

Supports hippocampal synaptic plasticity.

Neuroprotection

Slows oxidative stress and neurodegenerative processes.

Focus & mood

BDNF / NGF rise; attention and emotional regulation improve.

Reconstitution

How to prepare, step by step

Important

Sterile technique required. Use bacteriostatic water (BAC) only. Never distilled or tap water.

  1. 01

    5 mg lyophilized vial + 2 ml bacteriostatic water

  2. 02

    Inject water slowly onto vial wall, NOT directly onto powder

  3. 03

    Wait 30 seconds, swirl gently (DO NOT shake)

  4. 04

    Storage: refrigerated (2–8°C), max 28 days

Quality indicators

How to recognize a pure peptide

Purity markers

4
  • White / off-white powder

    Typical appearance of sterile lyophilized peptide.

  • Comes with COA (Certificate of Analysis)

    Independent lab analysis, ≥98% purity.

  • Intact, sealed vial

    Rubber stopper + aluminum crimp intact, ensuring sterility.

  • Dissolves clear

    Clear solution after reconstitution, no sediment.

Use caution

1
  • Storage temperature

    Extended room-temp exposure may reduce potency.

Do not use

2
  • Discoloration / sediment

    Yellow, cloudy or particulate solution, indicates degradation, do not use.

  • Damaged packaging

    Cracked vial or loose cap, sterility compromised, discard.

Interactions & stacks

What to combine and what to avoid

Adalank (NA Selank Amidate)

Synergistic

Stabilised Selank, anxiolytic + nootropic

Semax

Synergistic

ACTH(4-10) analog, nootropic nasal spray

Lion's Mane

Synergistic

Complementary NGF / BDNF pathway activation.

Vitamin C / Zinc / B-complex

Synergistic

Supports collagen synthesis and antioxidant capacity.

Modafinil

Requires timing

Combine in the morning; monitor for psychoactive interactions.

Caffeine

Requires timing

Compatible with morning dosing; avoid late-day stacking.

NSAIDs (Ibuprofen, ASA)

Use caution

Long-term concurrent use may blunt regenerative effects.

Alcohol

Avoid

Reduces recovery and increases side-effect risk.

Safety

Side effects, stop signs, contraindications

Side effects · 4

  • Headache, dizziness (during titration)
  • Transient mood shift
  • Sleep disturbance (if dosed late)
  • Mild injection-site irritation

Contraindications · 5

  • Pregnancy and breastfeeding
  • Active malignancy
  • Known allergy to the peptide or its components
  • Severe hepatic or renal impairment (medical consultation required)
  • Age under 18

Related Peptides

Same therapeutic category

Studies

Related research and clinical findings

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MolekulaX Editorial Team·Source-verified · PubMed · FDA · EMA
Updated: June 19, 2026

The information here is strictly for educational and scientific purposes. It does not replace medical advice or clinical consultation, and it does not encourage illegal substance or pharmaceutical use. Data is sourced. When in doubt, consult your doctor.